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Mesalamine is a prescription medication that's used to treat ulcerative colitis in adults. Ulcerative colitis is a type of inflammatory bowel disease. It causes inflammation (swelling) and small sores called ulcers in the lining of your colon and rectum. Mesalamine belongs to a class of drugs called aminosalicylates. Aminosalicylates are thought to reduce the inflammation in your bowel. Check out the price list of most popular Mesalamine generics and click on the product you want to purchase.