What is Pemnat 500 mg Injection ?
Pemnat 500 mg manufactured by Natco contains “Pemetrexed” as an active ingredient. This medication comes as a solution that is injected into a vein (intravenous). It is administered under the supervision of a qualified physician experienced in the use of antineoplastic therapy. Do not share Pemnat with others for whom it was not prescribed.
Pemnat 500 mg Injection Uses :
Pemnat (Pemetrexed) is used with another anti-cancer medicine to treat malignant pleural mesothelioma (A tumour of the tissue that lines the lungs, stomach, heart and other organs). It is also indicated to treat non-small cell lung cancer (NSCLC).
Pemnat Pemetrexed 500 mg Injection Works :
Pemetrexed belongs to a class of drugs known as antifolates. It interferes with cell metabolic processes that are dependent on folate and are required for cell replication. Premetrexed inhibits three enzymes that are required for purine and pyrimidine synthesis. These three enzymes are thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyl transferase (GARFT). When Premetrexed inhibits the formation of precursor purine and pyrimidine nucleotides, it prevents the formation of DNA and RNA required for growth and survival of both cancer and normal cells.
Pemnat 500 mg Injection Side – Effects :
This medicine may have some side effects, but not everyone will experience them. When you recommended Pemnat, it’s important to understand the side effects which you can experience from this cancer medicine. The following is a list of possible side-effects that may occur :
Common Side Effects : Diarrhea ; Fever ; Irritability ; Low Energy ; Muscle Pain ; Rash ; Feel Like Throwing Up ; Chronic Trouble Sleeping ; Itchiness ; Head Pain ; Loss Of Appetite ; Depression etc
Serious Side Effects : Fast or pounding heartbeat ; Changes in the amount of urine ; Dark urine ; Severe stomach or abdominal pain ; Yellowing eyes or skin ; Sore throat ; Painful or difficult swallowing ; Easy bruising or bleeding ; Numbness or tingling of the hands or feet etc.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Pemnat 500 mg – Storage Details :
Patients must properly store the drug to retain its quality and efficacy. Following storage instructions will be helpful in storing the drug in the best of manner.
• Store intact vials at room temperature of 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Reconstituted solution and infusion solution are stable for 24 hours when refrigerated at 2°C to 8°C (36°F to 46°F).
• When you aren’t injecting, store Pemnat vial in a place that’s protected from light.
• Make sure to always keep your medicine in an area of your home that is out of the reach of children and pets.
• Do not use Pemetrexed if the liquid in the vial looks discolored or cloudy, or if the liquid has lumps, flakes, or particles.
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The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.
Remember, keep this and all other medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.